Fat freezing complications may be more common than thought

Complications from the ‘fat freezing’ procedure that Linda Evangelista had may be more common than thought.

The supermodel revealed last week that she was left disfigured and distressed, but surgeons say she the procedure she underwent has risks for more people than previously thought.

Cryolipolysis is a noninvasive cosmetic procedure that eliminates excess fat by freezing it. But a complication called paradoxical adipose hyperplasia (PAH) – a hardened area of localized fat developing after cryolipolysis – may be more common than previously thought, suggests a paper in the July issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

While PAH can be treated successfully with liposuction, patients must wait a few months before treatment, according to the study, led by ASPS Member Surgeons Michael E. Kelly, MD, and Jose Rodríguez-Feliz, MD, of Miami Plastic Surgery. “Surgeons must be extremely sensitive when dealing with patients who have PAH, both when explaining the problem and when offering them a potential surgical solution,” the researchers write.

PAH after Cryolipolysis May Not Be a ‘Rare’ Complication

Drs. Kelly and Rodríguez-Feliz and colleagues share their experience in managing patients with PAH after cryolipolysis: an FDA-approved procedure that works by destroying cold-sensitive subcutaneous fat cells. It has become a popular technique for treating problem fat areas such as belly fat and “love handles.”

Paradoxical adipose hyperplasia has been reported as a rare adverse event after cryolipolysis. In this condition, the treated area becomes larger rather than smaller in the weeks after the procedure, leaving a “painless, visibly enlarged, firm, well-demarcated mass” under the skin. Based on data from the manufacturer of the cryolipolysis equipment, PAH has been estimated to occur in one out of every 4,000 treatment cycles, for an incidence of 0.025 percent.

The authors describe their experience with 11 patients with PAH. Six patients underwent cryolipolysis at the authors’ clinic and five were referred from other practices. The authors note that their experience of 15 PAH events in six patients represents a much higher incidence: 0.72 percent, or about 1 out of every 138 cryolipolysis treatments.

The good news is that PAH was successfully treated in all cases. Most patients needed liposuction only; one patient had liposuction combined with an abdominoplasty (“tummy tuck”) procedure. Dr. Rodríguez-Feliz recommend the use of a power-assisted liposuction technique. All patients achieved good cosmetic results and were very satisfied with their final appearance.

However, the patients had to wait several months for treatment. That time is needed for the fat in the area of PAH to soften; otherwise, there is a risk that PAH could recur. In some cases, more than one liposuction treatment was needed.

Drs. Kelly and Rodríguez-Feliz and colleagues acknowledge that it’s “very upsetting” for patients who initially sought a noninvasive fat reduction procedure to be faced with the need for an invasive procedure (liposuction) to correct the problem. Two patients with PAH refused further treatment, even though the treatment costs were covered by the manufacturer of the cryolipolysis equipment.

Patients are “initially aggravated by the delay and require continuing reassurance that the problem will ultimately be resolved,” the authors said. “Counselling is extremely important during this waiting period.”

“Despite these hurdles, patient satisfaction with the final surgical cosmetic result has been high,” Drs. Kelly and Rodríguez-Feliz and coauthors conclude.

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