Health officials confirmed the deceased, a man in his 60s, was being treated for cancer at Son Espases Hospital in Mallorca before dying of coronavirus.
As yet, it is not known how the man in palliative care contracted the virus.
Nineteen more people have been diagnosed with COVID19 in the Balearic Islands, bringing the total number of confirmed cases to 92. Sixty of these are in Mallorca.
A woman in her 50s with underlying health problems who died at Son Espases Hospital on March 12 was the first fatality.
Son Espases Hospital have not issued a statement on the latest death.