ONE of the first regions of the brain to be affected by Alzheimers disease is the entorhinal cortex (EC). Connections between the EC and the hippocampus are essential for memory. From the EC, mutated proteins spread throughout the neuron network to other parts of the brain.
Lead author of the study that discovered this, Dr Lennart Mucke, suggested that targeting the EC in the early stages of dementia could prevent the disease from spreading.
The study was done by scientists at the Gladstone Institute of Neurological Disease in San Francisco.