Yesterday the ‘In Da Club’ music star released his album, which is titled 'Animal Ambition: An Untamed Desire to Win'.
The star, who has also been in a number of Hollywood films and sold over 30 million records worldwide, has been unable to live up to the success of his debut album, 'Get Rich Or Die Tryin’.
In a Reddit AMA (Ask Me Anything) session the ‘Candy Shop’ singer said: "Technology is what's changing the business gotta get with it. I take money no matter if it's coins or dollars."
In response to the news Bitcoin magazine said: "There could not be a better combination of innovation in music and payment. We look forward to seeing which other musicians follow suit."
The album is available for purchase at shop.50cent.com using BitPay, a payment service which handles bitcoin transactions.
Currently one bitcoin is worth £430.